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JOM

Posterior cortical atrophy

By JOM Staff

01.19.23

A 64-year-old man presented to the neurology clinic in June 2021 after he developed progressive visual and cognitive decline over 2 years, including errors at work, peripheral vision loss, and dependence on family members for daily activities. Examination revealed disorientation to location and time; impaired reading, memory, and calculation; and bitemporal hemianopsia. Brain magnetic resonance imaging, reversible dementia work-up, and neuro-ophthalmologic evaluation were unremarkable. Fluorodeoxyglucose (FDG) positron emission tomography (PET) revealed bilateral parietooccipital hypometabolism with otherwise preserved lobar FDG avidity, suspicious for posterior cortical atrophy (PCA) (Figure 1, arrows).