Annular bullous lesions in a child from Uganda: chronic bullous disease of childhood

By JOM Staff

03.13.23

A 10-year-old male presented to our global outreach clinic in Uganda in May 2018 with a recurrent pruritic blistering rash on the lower leg of 1 year in duration. His medical history was unremarkable for autoimmune conditions or exposure to medications. Cutaneous examination showed urticarial plaques and numerous tense bullae in an annular arrangement on the left lower leg (Figure 1). Direct immunofluorescence (DIF) demonstrated a linear band of IgA at the dermoepidermal junction, consistent with a diagnosis of chronic bullous disease of childhood (CBDC). Oral dapsone was initiated with full resolution over the following week.

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