Idiopathic linear IgA bullous dermatosis with mucosal involvement

A 62-year-old woman presented to the hospital in July 2021 with a diffuse blistering rash. She had been suffering with limited cutaneous involvement for several years, which significantly worsened over a 2-month period which prompted her hospital admission. Cutaneous examination revealed diffuse tense vesicles and bullae in an annular arrangement on the arms, legs, trunk, ocular mucosa, and oral mucosa (Figures 1 and 2). Direct immunofluorescence (DIF) revealed linear IgA deposited along the basement membrane zone (BMZ). Medication reconciliation was unremarkable for any causative agents. The patient was diagnosed with idiopathic linear IgA bullous dermatosis (LABD) and initiated on oral dapsone with full resolution within the following week.

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